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oncogene    音标拼音: ['ɑŋkodʒ,in]
癌基因; 肿瘤基因

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  • Oncogene - Wikipedia
    An oncogene may cause a cell to secrete growth factors even though it does not normally do so It will thereby induce its own uncontrolled proliferation (autocrine loop), and proliferation of neighboring cells, possibly leading to tumor formation
  • Oncogene - National Human Genome Research Institute
    An oncogene is a mutated gene that has the potential to cause cancer Before an oncogene becomes mutated, it is called a proto-oncogene, and it plays a role in regulating normal cell division
  • Oncogene: What They Are What They Do - Cleveland Clinic
    It’s a mutated (changed) form of a normal gene, called a proto-oncogene, that manages cell growth When proto-oncogenes mutate into oncogenes, they cause cells to grow and divide uncontrollably
  • Oncogene | Description, Discovery, Proto-oncogene, Cancer, Facts . . .
    An oncogene is a sequence of deoxyribonucleic acid (DNA) that has been altered or mutated from its original form, the proto-oncogene Operating as a positive growth regulator, the proto-oncogene is involved in promoting the differentiation and proliferation of normal cells
  • Oncogenes, Tumor Suppressor Genes, and DNA Repair Genes
    When a proto-oncogene mutates (changes) or there are too many copies of it, it can become turned on (activated) when it is not supposed to be, at which point it's now called an oncogene When this happens, the cell can start to grow out of control, which might lead to cancer
  • Oncogenes and tumor suppressor genes: functions and roles in cancers
    Zuo T, Wang L, Morrison C, et al FOXP3 is an X‐linked breast cancer suppressor gene and an important repressor of the HER‐2 ErbB2 oncogene Cell 2007;129 (7):1275‐1286
  • Oncogene: Role in Cancer, Types, and Examples - Verywell Health
    If a mutation does occur, the gene can start to "turn on" in an uncontrolled manner, at which point it is called an oncogene Unlike proto-oncogenes, an oncogene will not turn off when it should As a result, cells can grow out of control, potentially leading to the growth of a cancerous tumor
  • Oncogenes | Springer Nature Link
    What Is an Oncogene? An oncogene is a mutated form of a normal cellular gene—called a proto-oncogene —that contributes to the development of a cancer Proto-oncogenes typically regulate basic processes that direct cell growth and cell differentiation





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